Monday, June 15, 2009

Summary of abiogenesis breakthroughs

Following up on an item from last month, the NYT has a great summary of the four principal features of new origins-of-life models:
  1. Discovery of the natural synthesis of fatty acids that spontaneously form membranes
  2. Discovery of a route of natural formation of nucleotides
  3. Discovery of RNA enzymes made solely from RNA
  4. Discovery of a solution to the chiral "problem"
Quote,

With these four recent advances — Dr. Szostak’s protocells, self-replicating RNA, the natural synthesis of nucleotides, and an explanation for handedness — those who study the origin of life have much to be pleased about, despite the distance yet to go. “At some point some of these threads will start joining together,” Dr. Sutherland said. “I think all of us are far more optimistic now than we were five or 10 years ago.”

One measure of the difficulties ahead, however, is that so far there is little agreement on the kind of environment in which life originated. Some chemists, like Günther Wächtershäuser, argue that life began in volcanic conditions, like those of the deep sea vents. These have the gases and metallic catalysts in which, he argues, the first metabolic processes were likely to have arisen.

But many biologists believe that in the oceans, the necessary constituents of life would always be too diluted. They favor a warm freshwater pond for the origin of life, as did Darwin, where cycles of wetting and evaporation around the edges could produce useful concentrations and chemical processes.
Great stuff. I love learning more about abiogenesis.